FORM 5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Form 3 Holdings Reported
Form 4 Transactions Reported
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0362
Estimated average burden hours per response... 1.0

1. Name and Address of Reporting Person *
Emerald Health Sciences Inc.
 2. Issuer Name and Ticker or Trading Symbol
Skye Bioscience, Inc. [SKYE] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)

OFFICE 8262, THE LANDING, 200-375 WATER ST.		 3. Statement for Issuer's Fiscal Year Ended (Month/Day/Year)
12/31-05:00/2021
(Street)


VANCOUVER, A1 V6B 0M9		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Reporting
(check applicable line)

_X_ Form Filed by One Reporting Person
___ Form Filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned at end of Issuer's Fiscal Year
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Amount (A) or (D) Price
Common Stock 08/07-05:00/2020   S(1) 2,566,666 D $ 0.1 111,387,251 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 2270 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
(A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Warrants with Credit Facility of Oct 5, 2018 $ 0.5 11/01-05:00/2018   A(1) 2,500,000   11/01-05:00/2018 11/01-05:00/2023 Common Stock
2,500,000
$ 0 2,500,000
D
 
Warrants with Credit Facility of Oct 5, 2018 $ 0.5 02/01-05:00/2019   A(1) 2,500,000   02/01-05:00/2019 02/01-05:00/2024 Common Stock
2,500,000
$ 0 2,500,000
D
 
Warrants with Credit Facility of Oct 5, 2018 $ 0.5 03/29-05:00/2019   A(1) 2,500,000   03/29-05:00/2019 03/29-05:00/2024 Common Stock
2,500,000
$ 0 2,500,000
D
 
Multi Draw Credit Facility - T2 $ 0.4 02/01-05:00/2019   A(1) 38,822   10/05-05:00/2022 10/05-05:00/2022(2) Common Stock
38,822
$ 0 38,822
D
 
Multi Draw Credit Facility - T3 $ 0.4 03/29-05:00/2019   A(1) 5,354,861   10/05-05:00/2022 10/05-05:00/2022(2) Common Stock
5,354,861
$ 0 5,354,861
D
 

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Emerald Health Sciences Inc.
OFFICE 8262
THE LANDING, 200-375 WATER ST.
VANCOUVER, A1 V6B 0M9		     X    

Signatures

/s/ Stephen Hall 01/31-05:00/2022
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Transactions were previously reported on various prior Form 4 filings; however, the entries were erroneously reported as non-derivative transactions in Common Stock and the resulting reported total ownership included the misclassified securities. The entry of these transactions is to correct this error and reflect the actual securities held by the Reporting Person.
(2) The Multi Draw Credit Facility tranches have the option to convert into Common Stock upon maturity of the facilities.

Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.