Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY

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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
Total
Prefunded Warrants
Series B - warrant liability
Common Stock
Common Stock
Prefunded Warrants
Common Stock
Series B - warrant liability
Additional Paid-In Capital
Additional Paid-In Capital
Series B - warrant liability
Accumulated Deficit
Balance (in shares) at Dec. 31, 2019       182,895,247          
Balance at Dec. 31, 2019 $ 548,058     $ 182,895     $ 32,538,445   $ (32,173,282)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Stock-based compensation expense 302,742           302,742    
Issuance of common stock and warrants, net of issuance costs (in shares)       56,333,334          
Issuance of common stock and warrants, net of issuance costs 6,085,589     $ 56,333     6,029,256    
Warrant exercises (in shares)   48,533,334     48,533,334 312,500      
Warrant exercises   $ 48,533 $ 26,563   $ 48,533 $ 313   $ 26,250  
Net loss and comprehensive loss (6,560,699)               (6,560,699)
Balance (in shares) at Dec. 31, 2020       288,074,415          
Balance at Dec. 31, 2020 450,786     $ 288,074     38,896,693   (38,733,981)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Stock-based compensation expense (in shares)       1,350,000          
Stock-based compensation expense 856,206     $ 1,350     854,856    
Issuance of common stock and warrants, net of issuance costs (in shares)       58,111,112          
Issuance of common stock and warrants, net of issuance costs 6,062,774     $ 58,111     6,004,663    
Warrant exercises (in shares)   11,800,000     11,800,000 116,666,668      
Warrant exercises   $ 11,800 $ 6,999,999   $ 11,800 $ 116,666   $ 6,883,333  
Exercise of stock options (in shares)       106,250          
Exercise of stock options 4,783     $ 107     4,676    
Net loss and comprehensive loss (8,522,182)               (8,522,182)
Balance (in shares) at Dec. 31, 2021       476,108,445          
Balance at Dec. 31, 2021 $ 5,864,166     $ 476,108     $ 52,644,221   $ (47,256,163)