Subsidiaries of the Registrant

Name of Entity			Formation Date			Jurisdiction of Incorporation			Holder of Stock
Nemus			July 17, 2012			California, USA			Skye Bioscience, Inc.
Skye Bioscience Pty Ltd.			August 9, 2019			Australia			Skye Bioscience, Inc.
Emerald Health Therapeutics, Inc.			July 31, 2007			British Columbia, Canada			Skye Bioscience, Inc.
Avalite Sciences, Inc.			March 3, 2005			British Columbia, Canada			Emerald Health Therapeutics, Inc.
Verdelite Sciences, Inc.			August 19, 2013			Quebec, Canada			Emerald Health Therapeutics, Inc.