Annual report pursuant to Section 13 and 15(d)

Warrants and Derivative Liabilities - Narrative (Details)

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Warrants and Derivative Liabilities - Narrative (Details) - USD ($)
 1 Months Ended 12 Months Ended
Sep. 29, 2021
Jul. 26, 2021
Aug. 04, 2020
Sep. 30, 2021
Jul. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Aug. 31, 2020
Class of Warrant or Right [Line Items]                
Decrease in derivative liability through an adjustment to change in fair value of derivative liabilities           $ 0    
August 2020 Financing                
Class of Warrant or Right [Line Items]                
Gross proceeds of warrants on a relative fair value basis     $ 6,939,667          
August 2020 Financing | Common Stock                
Class of Warrant or Right [Line Items]                
Gross proceeds of warrants on a relative fair value basis     $ 2,024,903          
2021 Inducement Warrants                
Class of Warrant or Right [Line Items]                
Exercise price (in dollars per share)   $ 0.06       $ 0.15    
2021 Inducement Warrants | July 2021 Inducement Warrants                
Class of Warrant or Right [Line Items]                
Number of shares issued in transaction (in shares)   21,166,667     21,166,667      
Common stock warrants         $ 2,790,884      
Exercise price (in dollars per share)   $ 0.15            
2021 Inducement Warrants to Placement Agent                
Class of Warrant or Right [Line Items]                
Exercise price (in dollars per share)           0.19    
2021 Inducement Warrants to Placement Agent | July 2021 Inducement Warrants                
Class of Warrant or Right [Line Items]                
Number of shares issued in transaction (in shares)         1,481,667      
Common stock warrants         $ 192,224      
2021 Common Stock Warrants                
Class of Warrant or Right [Line Items]                
Exercise price (in dollars per share)           0.09    
2021 Common Stock Warrants | September 2021 Financing                
Class of Warrant or Right [Line Items]                
Number of shares issued in transaction (in shares) 77,777,779              
Number of common stock warrant ( in shares)       77,777,779        
Proceeds to common stock warrants       $ 3,265,676        
Exercise price (in dollars per share) $ 0.09              
2021 Pre-Funded Warrants | September 2021 Financing                
Class of Warrant or Right [Line Items]                
Number of shares issued in transaction (in shares) 19,666,667              
Number of common stock warrant ( in shares)       19,666,667        
Proceeds to common stock warrants       $ 943,489        
Exercise price (in dollars per share) $ 0.0001              
2021 Common Stock Warrants to Placement Agent                
Class of Warrant or Right [Line Items]                
Exercise price (in dollars per share)           0.11    
2021 Common Stock Warrants to Placement Agent | September 2021 Financing                
Class of Warrant or Right [Line Items]                
Common stock warrants       $ 421,522        
Number of common stock warrant ( in shares)       5,444,445        
Common Stock Warrants | August 2020 Financing                
Class of Warrant or Right [Line Items]                
Number of warrants issued (in shares)     116,666,668          
2020 Common Stock Warrants to Placement Agent                
Class of Warrant or Right [Line Items]                
Exercise price (in dollars per share)           $ 0.08    
2020 Common Stock Warrants to Placement Agent | August 2020 Financing                
Class of Warrant or Right [Line Items]                
Number of warrants issued (in shares)     8,166,667          
Value of warrants issued recorded as equity issuance costs within equity     $ 261,333          
Prefunded Warrants | August 2020 Financing                
Class of Warrant or Right [Line Items]                
Number of warrants issued (in shares)     60,333,334          
Gross proceeds of warrants on a relative fair value basis     $ 2,146,997          
Exercise price (in dollars per share)     $ 0.001          
Common Stock Warrants | August 2020 Financing                
Class of Warrant or Right [Line Items]                
Gross proceeds of warrants on a relative fair value basis     $ 2,767,767          
Exercise price (in dollars per share)     $ 0.06          
Emerald Financing Warrant Liability                
Class of Warrant or Right [Line Items]                
Exercise price (in dollars per share)               $ 0.10
Series B Warrant Liability                
Class of Warrant or Right [Line Items]                
Number of warrants issued (in shares)             312,500  
Exercise price (in dollars per share)             $ 0  
Value of common stock called by warrants             $ 26,563  
Warrants to purchase shares of common stock issued and outstanding (in shares)             312,500