Annual report pursuant to Section 13 and 15(d)

Significant Contracts - University of Mississippi (Details)

v3.22.1
Significant Contracts - University of Mississippi (Details) - University of Mississippi
$ in Thousands
 1 Months Ended
May 24, 2019
USD ($)
Mar. 31, 2020
USD ($)
Jul. 31, 2018
Jan. 31, 2017
USD ($)
Dec. 31, 2021
milestone
UM 5050 Pro-Drug And UM 8930 Analog Agreements          
University Of Mississippi Agreements [Line Items]          
Annual maintenance fee payable $ 75        
Term of agreement     1 year    
Royalty obligation, expiration term     10 years    
Notice period for termination     60 days    
Number of milestones met | milestone         0
UM 5050 Pro-Drug And UM 8930 Analog Agreements | Milestone 1          
University Of Mississippi Agreements [Line Items]          
Aggregate milestone payments if milestones achieved $ 100        
Term of agreement 30 days        
UM 5050 Pro-Drug And UM 8930 Analog Agreements | Milestone 2          
University Of Mississippi Agreements [Line Items]          
Aggregate milestone payments if milestones achieved $ 200        
Term of agreement 30 days        
UM 5050 Pro-Drug And UM 8930 Analog Agreements | Milestone 3          
University Of Mississippi Agreements [Line Items]          
Aggregate milestone payments if milestones achieved $ 400        
Term of agreement 30 days        
UM 5050 pro-drug agreements          
University Of Mississippi Agreements [Line Items]          
Payment for upfront fees $ 100        
UM 8930 analog agreements          
University Of Mississippi Agreements [Line Items]          
Payment for upfront fees $ 200        
Annual fees for license agreement   $ 200      
UM 5070 license agreement          
University Of Mississippi Agreements [Line Items]          
Annual maintenance fee payable       $ 25  
Annual fees for license agreement       65  
Aggregate milestone payments if milestones achieved       $ 700  
Royalty obligation, expiration term       10 years  
Notice period for termination       60 days  
Number of milestones met | milestone         0