Annual report pursuant to Section 13 and 15(d)

Income Taxes - Provision for Income Taxes on Earnings (Details)

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Income Taxes - Provision for Income Taxes on Earnings (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Expected income tax benefit at federal statutory tax rate $ (1,789,217) $ (1,377,411)
State income taxes, net of federal benefit (475,287) (415,249)
Change in fair value of warrants 4,445 (72,549)
Change in valuation allowance 1,783,362 1,383,765
Uncertain tax positions 557,016 470,838
Non-deductible interest 36,731 33,925
Stock compensation 31,863 64,273
Research and development credits (168,514) (108,649)
Rate adjustment 785 0
Other permanent difference 20,916 22,657
Provision for income taxes $ 2,100 $ 1,600